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Other Name(s):A-Chymotrypsin, A-Chymotrypsine, Alpha-Chymotrypsin, Alpha-Chymotrypsine, Chymotrypsin A, Chymotrypsine A, Chymotrypsin B, Chymotrypsine B, Chymotrypsine, Chymotrypsinum, L-Chymotrypsin, L-Chymotrypsine, Quimotripsina.

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Chymotrypsin is an enzyme. An enzyme is a substance that speeds up certain chemical reactions in the body. People use chymotrypsin to lớn make medicine.

People take chymotrypsin by mouth or as a shot to reduce redness and swelling associated with pockets of infection (abscesses), ulcers, surgery, or traumatic injuries; và to help loosen phlegm in asthma, bronchitis, lung diseases, & sinus infections.

It is also taken by mouth khổng lồ reduce liver damage in burn patients; & khổng lồ assist in wound repair.

Chymotrypsin is sometimes breathed in (inhaled) or applied khổng lồ the skin (used topically) for conditions that involve sầu pain & swelling (inflammation) & for infections.

During cataract surgery, chymotrypsin is sometimes used lớn reduce damage to the eye.

How does it work?

Chymotrypsin has ingredients that reduce swelling (inflammation) and tissue destruction.


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Uses và Effectiveness


Effective sầu for...

Cataract surgery, when used by a healthcare professional.

Possibly Effective for...

Burns. There is some evidence that chymotrypsin might decrease tissue destruction in burn patients.Hand Fractures. Taking chymotrypsin by mouth seems to be effective sầu for reducing redness & swelling associated with hvà fractures.

Insufficient Evidence lớn Rate Effectiveness for...

Asthma.Bronchitis.Lung diseases.

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Sinus infections.Other conditions.More evidence is needed to lớn rate the effectiveness of chymotrypsin for these uses.

Natural Medicines Comprehensive sầu Database rates effectiveness based on scientific evidence according lớn the following scale: Effective, Likely Effective sầu, Possibly Effective sầu, Possibly Ineffective sầu, Likely Ineffective sầu, & Insufficient Evidence lớn Rate (detailed mô tả tìm kiếm of each of the ratings).


Side Effects


Chymotrypsin is safe when used in the eye by a healthcare professional. Chymotrypsin can cause side effects when used in the eye, including an increase in pressure in the eye & other eye conditions such as uveitis, paralysis of the iris, and keratitis.

It also seems lớn be safe for most people when taken by mouth to reduce redness and swelling following surgery or injury, and when applied directly to lớn the skin for burns.

Not enough is known about the safety of chymotrypsin for its other uses.

Rarely, chymotrypsin might cause an allergic reaction when taken by mouth. Symptoms include itching, shortness of breath, swelling of the lips or throat, shoông xã, loss of consciousness, & death.

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Special Precautions và Warnings


Pregnancy & breast-feeding: Not enough is known about the use of chymotrypsin during pregnancy & breast-feeding. Stay on the safe side and avoid use.


Dosing


The following doses have sầu been studied in scientific research:

BY MOUTH:To reduce tissue damage in burn patients: a 6:1 ratio (trypsin:chymotrypsin), in a combined amount of 200,000 units USPhường four times daily for ten days.BY INJECTION:Healthcare providers inject a solution of chymotrypsin inkhổng lồ the eyes as part of cataract surgery.


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Report Problems lớn the Food và Drug Administration

You are encouraged to report negative sầu side effects of prescription drugs to lớn the FDA. Visit the FDA MedWatch trang web or Gọi 1-800-FDA-1088.


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References

Dukes, MNG. Meyler"s Side Effects of Drugs. 13th ed. Elsevier: Amsterdam, 1997.

Latha B, Ramakrishnan M, Jayaraman V, Babu M. Serum enzymatic changes modulated using trypsin: chymotrypsin preparation during burn wounds in humans. Burns 1997;23:560-4. View abstract.

Latha B, Ramakrishnan M, Jayaraman V, Babu M. The efficacy of trypsin: chymotrypsin preparation in the reduction of oxidative sầu damage during burn injury. Burns 1998;24:532-8. View abstract.

McCue FC, Webster TM, Gieck J. Clinical effects of proteolytic enzymes after reconstructive hvà surgery. Int Surg 1972;57:479-82.

Shaw PC. The use of a trypsin-chymotrypsin formulation in fractures of the hand. Br J Clin Pract 1969;23:25-6.


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